COMPARE-UF

What is COMPARE-UF?

• The Comparing Options for Management: Patient Centered Results for Uterine Fibroids (COMPARE-UF) is a voluntary registry of 10,000 women with uterine fibroids that seeks to answer questions that matter most to patients with fibroids when considering the pros and cons of different treatment options. 
• To help women make treatment decisions, COMPARE-UF will collect information from participants about their medical history, planned and previous treatment for their fibroids, current symptoms, and quality of life.

What does COMPARE-UF involve?

• Women will be recruited from 9 clinical centers across the United States. The University of North Carolina at Chapel Hill will serve as 1 of the 9 recruitment sites and a diverse group of women will be recruited from central North Carolina and its surrounding areas.
• All women in COMPARE-UF will have fibroids formally diagnosed by a doctor through medical imaging and all treatment decisions will be made by the patient and her clinician.
• COMPARE-UF will: 1) compare different management options’ impact on symptom relief; 2) compare different management options’ impact on reproductive function; and 3) compare the effectiveness of the different management options among subgroups of patients, taking into account patient needs and treatment option preferences.

• Data will be collected from patients immediately prior to treatment determination and post-treatment (over the course of 5 years). The data collected will include procedural details (if applicable) and annual patient reported outcomes, including symptom relief, reproductive function, and quality of life.​
• Enrollment in COMPARE-UF will be launched in the fall of 2015.